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@article{190537,
        author = {Ishwari Ramdas Gangurde and Komal Jagannath More and Shreyas Tandale and Ankita Jha},
        title = {Gastroretentive Delivery of Herbal Anti-ulcer Agents: Design Strategies and Therapeutic Potential},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {8},
        pages = {2359-2366},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=190537},
        abstract = {Acid-related disorders such as hyperacidity, peptic ulcer disease, and gastroesophageal reflux disease (GERD) continue to affect a large portion of the population. Although conventional antacids and proton pump inhibitors are widely used, their prolonged use is often associated with limitations such as frequent dosing, reduced patient compliance, and potential adverse effects. Herbal anti-ulcer agents have gained attention due to their gastroprotective, antioxidant, and mucosal healing properties; however, their clinical effectiveness is often limited by insufficient gastric residence time (12,14,16). Gastroretentive drug delivery systems have emerged as a promising approach to enhance the therapeutic performance of drugs intended for local action in the stomach (1,2,8,15). This review focuses on the gastroretentive delivery of herbal anti-ulcer agents and discusses various formulation strategies including floating systems, mucoadhesive systems, in-situ gelling systems, and swellable matrices (4,17). In addition, commonly used herbal drugs, natural polymers, evaluation parameters, advantages, and formulation challenges are highlighted. The integration of herbal therapeutics with gastroretentive delivery platforms may offer a safer and more effective approach for the management of acid-related disorders (6,7).},
        keywords = {Gastroretentive drug delivery systems, Herbal anti-ulcer agents, Hyperacidity, Floating drug delivery, Mucoadhesive systems, Gastric retention},
        month = {January},
        }