Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
@article{190581,
author = {Rupali A. Mendake and Vijay M. Waghulkar and Monika P. Jadhao and Shailesh G. Jawarkar},
title = {TARGETING THE EYE: NOVEL STRATEGIES IN OCULAR DRUG TRANSPORT AND THERAPY},
journal = {International Journal of Innovative Research in Technology},
year = {2026},
volume = {12},
number = {8},
pages = {5171-5184},
issn = {2349-6002},
url = {https://ijirt.org/article?manuscript=190581},
abstract = {Many anatomical and physiological barriers affect how drugs are delivered to the eyes creating a bottleneck for ophthalmologists. The ocular barriers both static and dynamic limit the admission of xenobiotics and the absorption of therapeutic medicines. As a result, there are a number of drawbacks to using a typical ocular dose form to treat eye problems. The classification of ocular drug delivery methods and a general overview are covered in this review article along with examples of several traditional and modern formulations for ophthalmic drug delivery. Also included are constraints of traditional delivery with an eye towards finding cutting-edge methods including vesicular systems, nanotechnology, stem cell therapy as well as gene therapy oligonucleotide and aptamer therapy, protein and peptide delivery, and ribozyme therapy for treating various ocular illnesses. A high level of circulating drug would be necessary for systemic administration of a medicine to treat eye illness. Plasma to reach therapeutic concentrations.
The duration of the medicine's activity can be noticeably extended and the frequency of drug administration can be decreased by adopting prolonged drug delivery. Designing formulations like microspheres, nanoparticles, and liposomes that function as effective ocular drug delivery systems can help achieve this type of drug delivery. The scientists can regulate and create secure drug delivery systems with the aid of an update of study development in ocular drug delivery. This review article provides current information on several methods for administering the medication to the ocular region.},
keywords = {Ocular drug delivery; S.O.D.I; insert; minidisc; DED; Insert.},
month = {January},
}
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