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@article{190589,
        author = {Dr Priya Sudhesh and Bisni Fathima and Anoop S Nair},
        title = {BENTONITE –LACTIC ACID- TRANEXAMIC ACID COMPOSITE AS A SUSTAINABLE DRUG RELEASING HAEMOSTATIC AGENT},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {8},
        pages = {6112-6119},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=190589},
        abstract = {Fast-acting topical hemostatic agents are essential for effective bleeding control in emergency and surgical settings. Beyond rapid clot formation, the inhibition of fibrinolysis plays a crucial role in enhancing coagulation and improving survival outcomes. In the present study, intercalated composites of tranexamic acid–lactic acid–bentonite (TA–LA–bentonite) were synthesized to achieve sustained release for hemostatic applications. A simple, rapid, and reliable method was employed for the synthesis of these composite materials. The resulting compounds were comprehensively characterized using Fourier-transform infrared spectroscopy (FTIR), ultraviolet–visible (UV–Vis) spectroscopy, thermogravimetric and differential thermal analysis (TGA/DTA), scanning electron microscopy (SEM), and X-ray diffraction (XRD). The loading efficiency and pH-dependent release behavior of the active ingredient were quantitatively assessed using a colorimetric assay, in which ninhydrin served as the chromogenic reagent.},
        keywords = {Bentonite, lactic acid, drug delivery, tranexamic acid, haemostatic agent},
        month = {January},
        }