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@article{190772,
        author = {Virupakshaiah DBM and Abhishek N L and Shreekanth C S and Jasmin Rani},
        title = {IDENTIFICATION AND CHARACTERIZATION OF NEW DRUG TARGETS AGAINST GUT PATHOGENS USING BIOINFORMATICS APPROACH: A REVIEW},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {8},
        pages = {5077-5084},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=190772},
        abstract = {The microbiota is the collective term for the human body consists of vast number of bacteria, fungi, and other microbes that living in the human body. The human gut's ability to absorb, digest, and use nutrients, vitamins, and minerals is greatly influenced by the gut microbiota, which also affects other organ systems and functions. Lifestyle, sex, diet, age, and other genetic factors are all linked to the human gut microbiome, suggesting that the microbiome is shaped by host variables. The molecular and the cellular pathways of microbe–host interactions has been studied, it is increasingly being noticed that cross reactions between the host and its microbes can occur. The ongoing increase in pathogenic bacteria that are extremely resistant to a variety of antibiotics makes it extremely difficult to control pathogenic diseases. Drug research and discovery is a drawn-out and complex process that requires a significant time and financial commitment. In addition to speeding up the process of identifying therapeutic targets, screening, and improving drug candidates, bioinformatics tools and approaches can also make it easier to identify the adverse effects and anticipated drug resistance. The mechanics-based drug discovery and drug reuse, high-throughput data from transcriptomics, proteomics, or whole genomes and metabolomics are crucial. With this scenario, the present review of study aimed to describe and highlight on the bioinformatics approaches in drug research and development with regards to their roles in identification and characterization of new drug targets against gut pathogens.},
        keywords = {Gut microbiome, Bioinformatics, Drug targets, Druggability, Virtual screening},
        month = {January},
        }