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@article{190901,
author = {Gajbhiye R. G.},
title = {Environmentally Friendly Schiff Base–Metal Complexes: Promising Agents against Pathogens and Cancer Cells},
journal = {International Journal of Innovative Research in Technology},
year = {2026},
volume = {12},
number = {8},
pages = {4323-4329},
issn = {2349-6002},
url = {https://ijirt.org/article?manuscript=190901},
abstract = {A mixed ligand complex was synthesized using the Schiff base ligand p-Methoxy Isonitrosoacetophenone (p-MINAP), prepared by the reaction of p-Methoxyacetophenone with n-amyl nitrite, as the primary ligand, and 1,10-Phenanthroline (1,10-Phen) as the secondary ligand. The Schiff base ligand and the resulting mixed ligand complex were characterized through elemental analysis, IR, UV-Visible spectroscopy, ¹H NMR, molar conductance, and magnetic moment studies.
The mixed ligand complex was found to have the general formula [M(p-MINAP)(1,10-Phen)], with an octahedral geometry around the metal center. The synthesized Schiff base (p-MINAP), the 1,10-Phenanthroline ligand, and their mixed ligand complex were evaluated for antibacterial and antifungal activities against both Gram-positive and Gram-negative bacteria, as well as fungi. The results revealed significant antimicrobial activity of the synthesized compounds.},
keywords = {Schiff base, p-MINAP, 1,10-Phenanthroline, Mixed ligand complex.},
month = {January},
}
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