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@article{191123,
        author = {Supriya Yelba Gurme and Dr.Wadulkar R.D. and Satpute K.L. and Dorle Shubhangi Bhaurao and Parakh Yugraj Gyanchand and Rathod Vishal Ambadas},
        title = {EVALUATION OF SKELETAL MUSCLE RELAXANT ACTIVITY OF MUSA ACUMINATA PULP EXTRACT IN WISTER RATS.},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {8},
        pages = {6288-6296},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=191123},
        abstract = {Skeletal muscle relaxant activity of the methanolic fruit pulp extract of Musa Acuminata was investigated by testing the effect of the extract on Wistar rat. The evaluation of in-vivo skeletal muscle relaxant activity in rats was done using Rota rod model & Actophotometer model. Experiments were carried on female Wistar rats and the animals were randomly allotted to the different control and test groups. Musa acuminata has been broadly using as traditionally medicine in several countries. Taxonomically Musa Acuminata belong to family Musaceae. In the present study, pulp powder of Musa Acuminata were subjected to phytochemical evaluation.. The powdered plant material was extracted by Soxhlet extractor in methanol and acetone.
Phytochemical testing of extracts discovered presence of glycosides, flavonoids, carbohydrates, tannins, phenolic, flavonoids etc. Anti- oxidant activity was carried out by 2, 2- diphenyl-1-picrylhyrazyl (DPPH) assay. DPPH scavenging assay were performed to evaluate the antioxidant activity which was found maximum at 50 microgram concentration for methanolic extracts.
The extract was administered orally at a dose of 250mg/kg and 500mg/kg. Diazepam in a dose of 10 mg/kg (i.p) was used as a standard. The results showed that methanolic extract of Musa Acuminata shows significant skeletal muscle relaxant activity as compared to standard drug at the doses of 250mg/kg & 500mg/kg.},
        keywords = {Skeletal Muscle Relaxant activity, Musa Acuminata, Acto photometer, Rota rod apparatus, Muscle relaxant activity.},
        month = {January},
        }