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@article{191642,
        author = {Bonbon Preethi Raj and suvarna Dnyaneshwar ingole and Maturi.Akshitha goud and R.Vedamukhi and Thotapalli Likitha and Nerella Indira Rani and Hemalatha sattu},
        title = {Champaca Derived Anti infection A Review of Isolation Method and Antimicrobial Activities},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {8},
        pages = {7403-7413},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=191642},
        abstract = {Magnolia champaca, also known as Michelia champaca, is a flowering species in the Magnoliaceae family. It is known worldwide for its strong therapeutic value and important role in traditional medicine. This review examines the plant as a source of bioactive secondary compounds, including oxoaporphine alkaloids, flavonoids, and sesquiterpene lactones, which contribute to its potent anti-infection properties. Researchers isolate these active compounds using various methods like maceration, Soxhlet extraction, and microwave-assisted techniques with different solvents such as methanol, n-hexane, and chloroform. Advanced chromatography techniques, including Column Chromatography, High-Performance Liquid Chromatography, and Gas Chromatography-Mass Spectroscopy, help identify and purify key compounds such as Liriodenine, Parthenolide, and Tributyl acetylcitrate. Pharmacological studies show that these extracts have broad-spectrum antibacterial effects against human pathogens like Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa, often by disrupting cell membranes or causing oxidative stress. Additionally, bark extracts display strong antifungal activity against pathogens like Curvularia verruculosa, while sesquiterpene lactones from the flowers show significant antimalarial activity. The plant also has potential for the green synthesis of silver nanoparticles to improve antimicrobial effectiveness. Combining traditional knowledge with scientific isolation methods highlights M. champaca as a sustainable and effective source for creating new plant-based anti-infection agents.},
        keywords = {Magnolia champaca; Antimicrobial activity; Phytochemical profile; Extraction methods; Liriodenine; Natural products},
        month = {January},
        }