Formulation and Evaluation of a Herbal-Based Self-Healing Hydrogel for Chronic Wound Dressings such as Diabetic Ulcers: A Review

  • Unique Paper ID: 191646
  • Volume: 12
  • Issue: 8
  • PageNo: 7704-7711
  • Abstract:
  • Chronic wounds, particularly diabetic foot ulcers (DFUs), represent a significant global health burden due to their high prevalence, prolonged healing times, susceptibility to infection, and substantial socioeconomic impact. Traditional wound dressings often fall short in managing the complex microenvironment of diabetic ulcers. Recently, self-healing hydrogels have emerged as a promising class of biomaterials due to their ability to autonomously repair mechanical damage, maintain structural integrity, and provide a moist wound-healing environment. Incorporating herbal extracts—known for their anti-inflammatory, antimicrobial, antioxidant, and tissue-regenerative properties—into these hydrogels offers a synergistic strategy for enhancing wound repair. This review comprehensively synthesizes current research on the formulation and evaluation of herbal-based self-healing hydrogels for diabetic wound management. It discusses the therapeutic potential of key phytoconstituents, design principles for self-healing and stimuli-responsive hydrogels, fabrication techniques, characterization methodologies, and preclinical evidence of efficacy. Additionally, challenges in standardization, scalability, stability, and regulatory approval are addressed. The integration of natural herbal extracts within advanced hydrogel matrices presents a sustainable, biocompatible, and multifunctional approach with significant promise in accelerating the healing of chronic diabetic ulcers.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{191646,
        author = {Rishabh Singh and Dr. Sanjay Kumar Kushwaha},
        title = {Formulation and Evaluation of a Herbal-Based Self-Healing Hydrogel for Chronic Wound Dressings such as Diabetic Ulcers: A Review},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {8},
        pages = {7704-7711},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=191646},
        abstract = {Chronic wounds, particularly diabetic foot ulcers (DFUs), represent a significant global health burden due to their high prevalence, prolonged healing times, susceptibility to infection, and substantial socioeconomic impact. Traditional wound dressings often fall short in managing the complex microenvironment of diabetic ulcers. Recently, self-healing hydrogels have emerged as a promising class of biomaterials due to their ability to autonomously repair mechanical damage, maintain structural integrity, and provide a moist wound-healing environment. Incorporating herbal extracts—known for their anti-inflammatory, antimicrobial, antioxidant, and tissue-regenerative properties—into these hydrogels offers a synergistic strategy for enhancing wound repair. This review comprehensively synthesizes current research on the formulation and evaluation of herbal-based self-healing hydrogels for diabetic wound management. It discusses the therapeutic potential of key phytoconstituents, design principles for self-healing and stimuli-responsive hydrogels, fabrication techniques, characterization methodologies, and preclinical evidence of efficacy. Additionally, challenges in standardization, scalability, stability, and regulatory approval are addressed. The integration of natural herbal extracts within advanced hydrogel matrices presents a sustainable, biocompatible, and multifunctional approach with significant promise in accelerating the healing of chronic diabetic ulcers.},
        keywords = {Self-healing hydrogel, herbal extracts, diabetic ulcers, chronic wound healing, wound dressing, natural polymers, biocompatibility.},
        month = {January},
        }

Cite This Article

Singh, R., & Kushwaha, D. S. K. (2026). Formulation and Evaluation of a Herbal-Based Self-Healing Hydrogel for Chronic Wound Dressings such as Diabetic Ulcers: A Review. International Journal of Innovative Research in Technology (IJIRT), 12(8), 7704–7711.

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