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@article{192262,
author = {Dr Vinod Bhagwanrao Bhoyate Principal and Mr Kale Om Navnath and Miss Handal Swati Babasaheb and Miss Bade Aishwarya Ramesh and Miss Motakar Shital Dadasaheb},
title = {Formulation and Evaluation of Aloe Vera and Neem Cream for Skin Infections},
journal = {International Journal of Innovative Research in Technology},
year = {2026},
volume = {12},
number = {9},
pages = {801-811},
issn = {2349-6002},
url = {https://ijirt.org/article?manuscript=192262},
abstract = {Skin infections are common dermatological disorders caused mainly by bacteria and fungi, leading to symptoms such as itching, redness, inflammation, pain, and discomfort. The excessive use of synthetic topical preparations often results in adverse effects including skin irritation, allergic reactions, and microbial resistance. Therefore, there is an increasing demand for herbal formulations that are safe, economical, and effective. Aloe vera and Neem (Azadirachta indica) are well-known medicinal plants traditionally used for the treatment of skin disorders. Aloe vera exhibits wound healing and moisturizing properties, whereas Neem possesses strong antibacterial and antifungal activity.
The present study was aimed to formulate and evaluate a herbal cream containing Aloe vera and Neem extracts for skin infections. The cream was prepared using the oil-in-water emulsification technique and evaluated for physicochemical parameters such as pH, viscosity, spreadability, homogeneity, washability, skin irritation, and stability. Antimicrobial activity was evaluated using the agar well diffusion method against Staphylococcus aureus, Escherichia coli, and Candida albicans. The formulated cream showed acceptable physical properties, good stability, and significant antimicrobial activity. The study concludes that Aloe vera and Neem based herbal cream can be considered a safe and effective alternative for the management of skin infections.},
keywords = {Aloe vera, Neem, Herbal cream, Skin infections, Antimicrobial activity, Topical formulation},
month = {February},
}
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