Formulation and Evaluation of Nanoemulsion-Based Herbal Anti-Acne Gel

  • Unique Paper ID: 193191
  • Volume: 12
  • Issue: 9
  • PageNo: 4413-4419
  • Abstract:
  • Acne vulgaris is one of the most common dermatological disorders affecting adolescents and young adults worldwide. It is primarily caused by excessive sebum production, follicular hyperkeratinization, bacterial infection, and inflammation. Conventional anti-acne formulations such as antibiotics and retinoids are effective but often produce side effects including dryness, irritation, erythema, and microbial resistance. Therefore, herbal formulations incorporated into advanced drug delivery systems are gaining importance due to improved efficacy and safety. Nanoemulsion-based topical systems enhance drug penetration, stability, and bioavailability of herbal active constituents. The present study aimed to formulate and evaluate a nanoemulsion-based herbal anti-acne gel containing plant extracts with antimicrobial and anti-inflammatory properties. The nanoemulsion was prepared using high energy emulsification method and incorporated into a gel base. The formulation was evaluated for particle size, pH, viscosity, spreadability, drug content, stability, and antimicrobial activity against acne-causing bacteria. The results indicated that the developed nanoemulsion gel showed suitable physicochemical properties, good stability, and significant antimicrobial activity. The study concludes that nanoemulsion-based herbal gel can be considered a promising and safe alternative for the management of acne vulgaris.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{193191,
        author = {Najan Sumit Suresh and Shirsath Rameshwar Vishnu and Nikita Sanjay Salekar and Ubale Nikita Sudhakar and Gaikwad kirti Sudhakar},
        title = {Formulation and Evaluation of Nanoemulsion-Based Herbal Anti-Acne Gel},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {9},
        pages = {4413-4419},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=193191},
        abstract = {Acne vulgaris is one of the most common dermatological disorders affecting adolescents and young adults worldwide. It is primarily caused by excessive sebum production, follicular hyperkeratinization, bacterial infection, and inflammation. Conventional anti-acne formulations such as antibiotics and retinoids are effective but often produce side effects including dryness, irritation, erythema, and microbial resistance. Therefore, herbal formulations incorporated into advanced drug delivery systems are gaining importance due to improved efficacy and safety.
Nanoemulsion-based topical systems enhance drug penetration, stability, and bioavailability of herbal active constituents. The present study aimed to formulate and evaluate a nanoemulsion-based herbal anti-acne gel containing plant extracts with antimicrobial and anti-inflammatory properties. The nanoemulsion was prepared using high energy emulsification method and incorporated into a gel base. The formulation was evaluated for particle size, pH, viscosity, spreadability, drug content, stability, and antimicrobial activity against acne-causing bacteria. The results indicated that the developed nanoemulsion gel showed suitable physicochemical properties, good stability, and significant antimicrobial activity. The study concludes that nanoemulsion-based herbal gel can be considered a promising and safe alternative for the management of acne vulgaris.},
        keywords = {Nanoemulsion, Anti-acne gel, Herbal formulation, Topical drug delivery, Acne vulgaris, Nanotechnology},
        month = {February},
        }

Cite This Article

Suresh, N. S., & Vishnu, S. R., & Salekar, N. S., & Sudhakar, U. N., & Sudhakar, G. K. (2026). Formulation and Evaluation of Nanoemulsion-Based Herbal Anti-Acne Gel. International Journal of Innovative Research in Technology (IJIRT), 12(9), 4413–4419.

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