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@article{193855,
        author = {Dr. Kota Adinarayana and S.Bindu and C.H.Tejaswi Bhavani and K.Bhavitha and K.Usha Rani and D. Akbar vali},
        title = {A Comprehensive Review on Exploration of Bioactive Phytoconstituents and Anti- Cancer potential of the Selected Fabaceae Species},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {10},
        pages = {2134-2143},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=193855},
        abstract = {Cancer is the second leading cause of death worldwide, despite the availability of diverse treatment modalities such as surgery, chemotherapy, radiotherapy, immunotherapy, and targeted therapy. The limitations associated with these approaches including toxicity, drug resistance, and high costs have intensified the search for safer and more effective alternatives. In this context, phytochemicals have emerged as promising candidates for cancer prevention and therapy. These bioactive compounds exert anticancer effects through multiple mechanisms, including carcinogen inactivation, induction of cell cycle arrest, reduction of oxidative stress, stimulation of apoptosis, inhibition of angiogenesis, and modulation of immune responses. The family Fabaceae (Leguminosae) is the second largest and one of the most diverse families in the plant kingdom, with species widely distributed across tropical, subtropical, and temperate regions. Members of this family are rich sources of diverse phytochemicals such as flavonoids, lectins, saponins, alkaloids, carotenoids, and phenolic acids. These compounds have demonstrated a wide range of pharmacological activities, particularly anticancer potential, through antioxidant, anti-inflammatory, antiproliferative, and pro-apoptotic mechanisms. Despite the recognized therapeutic value of Fabaceae species, comprehensive exploration of their phytochemical profiles and anticancer mechanisms remains insufficient. Therefore, this review aims to consolidate and critically analyze the available information regarding the phytochemical composition of the Fabaceae family and their anticancer properties. Additionally, it highlights existing research gaps and proposes future directions to facilitate systematic investigation and translational development of Fabaceae derived anticancer agents.},
        keywords = {Cancer; Phytochemicals; Fabaceae; Flavonoids; Apoptosis; Anticancer activity.},
        month = {March},
        }