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@article{194324,
        author = {Shivani B. Malap and Raju M. Patil},
        title = {Nickel Complexes derived from Novel Phenylthiosemicarbazone ligands as Antimicrobial and Anticancer Agents: Synthesis, Characterization and Biological Investigations},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {10},
        pages = {3531-3550},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=194324},
        abstract = {The present study deals with synthesis of series of novel Nickel(II) complexes derived from Isonitrosoacetophenone-4-Phenylthiosemicarbazones. The newly synthesized complexes have been fully characterized by spectroscopic and physiochemical methods like elemental analysis, UV-Visible, FTIR, 1H-NMR, Conductivity, TG-DTA, Cyclic Voltammetry and Magnetic Suceptibility Measurements. XRD analysis has also been used as an additional method to learn about crystal symmetry. All the complexes appear to be in crystalline phases based on the XRD pattern. To study the electrochemical behaviour of Nickel(II) complex Cyclic voltammetry was used. This showed that the ligand peaks changed significantly and new peaks appeared after the complexation process. The complexes have also been studied for their biological activity against four selected bacterial strains for antibacterial activity and two fungal strains for its antifungal activity. According to antimicrobial investigation both antibacterial and antifungal activity of complexes was higher than those of the ligands.The Complexes have also been tested for its Anti cancer activity against MDA-MB-231 Breast cancer cell line.},
        keywords = {Isonitrosoacetophenones, 4-Phenylthiosemicarbazones, Polydentate ligands, Antimicrobial activity, Transition metal complexes.},
        month = {March},
        }