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@article{194360,
        author = {Gokila Devi S and Dinesh Kumar s and Shalini M},
        title = {Ex Vivo Therapeutic Assessment of Cardiospermum halicacabum Extract: A Dual Investigation on Cataract and Helminthic Infections},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {10},
        pages = {3315-3323},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=194360},
        abstract = {This research examines the therapeutic power of ethanolic Cardiospermum halicacabum extract on cataractogenesis and helminthic infections in ex vivo conditions. The plant underwent an authentication process before shade-drying for cold maceration extraction. A preliminary phytochemical examination showed that the extract contained alkaloids, together with flavonoids and carbohydrates and proteins and amino acids and glycosides and saponins and phenols, and tannins. Anthelmintic activity was evaluated using Indian adult earthworms, where the extract demonstrated significant, dose-dependent paralytic and lethal effects, comparable to the standard drug albendazole. The extract showed strong antioxidant and protective properties by reducing lens opacification in glucose-induced cataract goat lens models. The therapeutic effects of C. halicacabum validate its traditional use in medicine and demonstrate its potential as a natural treatment option. Additional studies using living organisms together with detailed mechanism analysis need to identify the active components while proving safety for clinical practice validation.},
        keywords = {Cardiospermum halicacabum, ethanolic extract, phytochemical screening, ex vivo evaluation, herbal therapeutics, anthelmintic activity, cataractogenesis, antioxidant activity.},
        month = {March},
        }