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@article{195152,
        author = {NASRIN HANEEFA and NIRNAYA AJOYKUMAR and NIVETHA SURESHKUMAR and NIJAVARTHINI SIVASAMI and MUBEENA RAHMAN and MUGHILAN RAJESHWARAN and NANDHINI BALASUBRAMANI and NANDHITHA VENKAT},
        title = {Radiation Therapy Unveiled : Oral Mucosal Changes, Histopathology,And Effects On Dentition And Histopathological Alteration.},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {10},
        pages = {6754-6759},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=195152},
        abstract = {Radiation therapy is a key modality in the management of head and neck malignancies, but it is associated with a range of oral complications that can significantly impair function and quality of life. Ionizing radiation induces both acute and chronic changes in oral tissues, particularly affecting the mucosa, taste buds, musculature, and bone. Acute effects are most commonly seen as mucositis, characterized by painful inflammation and ulceration of the oral mucosa, which interferes with eating, speech, and oral hygiene during treatment, along with taste disturbances such as dysgeusia, hypogeusia, and ageusia due to direct damage to taste receptors. Over time, chronic complications may develop, including mucosal atrophy, submucosal fibrosis, trismus resulting from muscular involvement, and osteoradionecrosis of the jaw, all of which contribute to long-term functional limitations. These adverse effects are largely dose-dependent and often require prolonged management; therefore, early dental evaluation, implementation of preventive strategies, and a coordinated multidisciplinary approach are essential to minimize complications and improve overall patient outcomes.},
        keywords = {Radiation therapy, Mucositis, Xerostomia, Dysgeusia, Dental caries and Osteoradionecrosis},
        month = {March},
        }