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@article{195153,
        author = {Ashwin Varadharajan and Babisha Sterlin Rajan and Arokiasubha Stalinmuthu and Dharani Palaniyappan and Dr. Deepshika saravanan},
        title = {NANOPARTICLES ENHANCED PHOTODYNAMIC THERAPY IN TREATMENT OF PERIODONTITIS},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {10},
        pages = {7647-7652},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=195153},
        abstract = {Periodontitis is a chronic inflammatory disease characterized by progressive destruction of the supporting structures of teeth. Conventional therapy, including scaling and root planing (SRP), may not completely eliminate pathogens in deep periodontal pockets. Photodynamic therapy (PDT) has emerged as a minimally invasive adjunctive approach that uses a photosensitizer activated by specific light wavelengths to generate reactive oxygen species, leading to targeted microbial destruction. However, limitations such as poor photosensitizer retention and limited light penetration reduce its long-term efficacy. Incorporating nanoparticles enhances PDT by improving drug delivery, biofilm penetration, ROS generation, and tissue targeting. Preclinical studies demonstrate improved antimicrobial, anti-inflammatory, and regenerative outcomes. In our study we are discussing about the applications of nanoparticle-enhanced PDT in periodontal therapy .},
        keywords = {Nanoparticles, Photodynamic therapy, Photosensitizer, Drug delivery , Reactive oxygen species, Adjunctive periodontal treatment.},
        month = {March},
        }