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@article{195494,
        author = {RESHMA SOUNDARARAJAN and RAMSEENA ABDUL KHADAR and PRIANKA JAYARAMAN and DR. DEEPSHIKA SARAVANAN and Dr.Maria Subash Aaron M and Dr.Vaishnavi S},
        title = {PLATELET-RICH FIBRIN IN PERIODONTAL REGENERATION},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {11},
        pages = {2170-2175},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=195494},
        abstract = {Platelet-rich Fibrin (PRF) has become a powerful autologous biomaterial in the field of periodontal regeneration, aiding the healing of both hard and soft tissues. This comprehensive review examines the biological mechanisms of PRF, its various forms, preparation methods, clinical uses in periodontal treatment, and its present limitations. PRF contributes to significant reductions in probing depths, gains in clinical attachment, and the filling of bone defects in both intrabony and furcation areas. While using PRF on its own provides beneficial results, its regenerative effects can be significantly improved when combined with bone grafts, bioactive biomolecules, or barrier membranes. By facilitating the gradual, sustained release of growth factors and creating a stable three-dimensional fibrin structure, PRF promotes osteogenesis, angiogenesis, and soft tissue healing. Continuous developments, including advanced PRF (A-PRF), injectable PRF (i-PRF), and standardized protocols for preparation, are anticipated to enhance its dependability and practical use in modern clinical dental practices.},
        keywords = {Platelet-rich fibrin (PRF), Periodontal regeneration, Intrabony defects, Bone regeneration, Growth factors, Regenerative dentistry},
        month = {April},
        }