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@article{195819,
        author = {Dr.Kranti A.Dale and Hansika M.Sulakhe},
        title = {Understanding PCOS: A Review of Its Causes, Symptoms, Pathogenesis, and Management Strategies},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {11},
        pages = {1107-1114},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=195819},
        abstract = {The aim of this review is to provide an overview on the polycystic ovarian syndrome (PCOS) including its causes, symptoms and management. The most prevalent endocrine and metabolic conditions affecting women in their reproductive years is PCOS. About 116 million women worldwide (3.4%) may be impacted by PCOS, according to data from the World Health Organization (WHO). This is a heterogeneous endocrine condition that manifests as insulin resistance, increased testosterone levels, swollen and malfunctioning ovaries, and other symptoms. This paper covers the information about the polycystic ovary syndrome, its causes, symptoms, pathogenesis and its management in brief. External causes include genetic mechanism, diet and environmental factors while insulin resistance, inflammation, hyperandrogenism and obesity are the internal causes. Irregular periods, hirsutism, acne & oily skin, mood swings, weight gain, heavy bleeding, hair thinning, diabetes, pelvic pain, sleep problems and skin darkening are the main signs and symptoms of the PCOS. Pathogenesis of PCOS involves alteration in insulin secretion, change in gonadotropin – releasing hormone and excess androgen level. When treating PCOS, more focus should be placed on the patient's adherence to treatment.},
        keywords = {polycystic ovary syndrome, hyperandrogenism, insulin resistance, molecular mechanisms, management, repurposing drugs.},
        month = {April},
        }