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@article{196493,
        author = {Karan R. Bhavsar and Zeeshan I. Ansari and Rashmi P. Ahire and Chetan D. Dhokare and Arshad M. Ansari and Raj H. Dode},
        title = {A COMPREHENSIVE REVIEW ON THE PREPARATION AND EVALUATION OF ORAL REHYDRATION SOLUTION FROM DATE (PHOENIX DACTYLIFERA) SEEDS},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {11},
        pages = {4727-4733},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=196493},
        abstract = {Oral Rehydration Solution (ORS) is a widely used and effective treatment for dehydration, especially in conditions like diarrhea. Traditionally, ORS is prepared using synthetic glucose and electrolyte mixtures. However, there is a growing interest in developing natural and more affordable alternatives. 
Date seeds, obtained from Phoenix dactylifera, are usually treated as waste, but they actually contain valuable nutrients such as potassium, sodium, magnesium, and various bioactive compounds like antioxidants and phenolics. Because of this rich composition, date seeds have the potential to be used as a natural source in ORS formulations. Along with restoring electrolyte balance, they may also offer additional benefits, including antioxidant, antimicrobial, and mild anti-diarrheal effects. 
The preparation of ORS using date seeds involves several steps such as cleaning, drying, grinding, and extracting the active components through methods like hot water extraction or decoction. To make the formulation more effective, glucose and certain salts can be added to match standard ORS requirements and improve absorption in the body. 
Studies have shown that date seed-based ORS has acceptable taste, suitable pH, balanced electrolyte content, and good rehydration ability, similar to conventional ORS. It also has added advantages like better palatability, improved nutritional value, lower cost, and eco-friendly utilization of waste materials. 
Despite these benefits, some challenges remain, including variations in seed composition, lack of proper standardization, limited clinical studies, and concerns about shelf life. Therefore, further research, including clinical trials and formulation improvements, is necessary. 
Overall, ORS prepared from date seeds appears to be a promising natural and sustainable alternative, particularly beneficial in areas with limited resources},
        keywords = {Oral Rehydration Solution (ORS), Date Seed, Phoenix dactylifera, Electrolytes, Natural Formulation, Dehydration, Herbal ORS},
        month = {April},
        }