OPTIMIZATION AND VALIDATION OF UV ANALYTICAL METHODS FOR FENOFIBRATE USING VARIOUS CALIBRATION TECHNIQUES

  • Unique Paper ID: 198399
  • Volume: 12
  • Issue: 11
  • PageNo: 11158-11164
  • Abstract:
  • UV spectrophotometric techniques play a crucial role in pharmaceutical analysis for the estimation of active compounds. This study presents the development and validation of a UV-Visible Spectroscopy method for Fenofibrate using methanol as a solvent. The method adheres to Beer-Lambert’s law and ICH guidelines, exhibiting a maximum absorbance at 290 nm. Excellent linearity (R² = 0.9994) was observed over the tested concentration range, with precise LOD and LOQ values confirming the method’s sensitivity. Additionally, the method demonstrated high precision, accuracy, and robustness, making it a reliable choice for routine pharmaceutical quality control applications.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{198399,
        author = {VISHAL VITTHAL NARSALE and rinku bhosale and vikesh kukade and shrikrishna baokar},
        title = {OPTIMIZATION AND VALIDATION OF UV ANALYTICAL METHODS FOR FENOFIBRATE USING VARIOUS CALIBRATION TECHNIQUES},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {11},
        pages = {11158-11164},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=198399},
        abstract = {UV spectrophotometric techniques play a crucial role in pharmaceutical analysis for the estimation of active compounds. This study presents the development and validation of a UV-Visible Spectroscopy method for Fenofibrate using methanol as a solvent. The method adheres to Beer-Lambert’s law and ICH guidelines, exhibiting a maximum absorbance at 290 nm. Excellent linearity (R² = 0.9994) was observed over the tested concentration range, with precise LOD and LOQ values confirming the method’s sensitivity. Additionally, the method demonstrated high precision, accuracy, and robustness, making it a reliable choice for routine pharmaceutical quality control applications.},
        keywords = {UV spectrophotometry, Fenofibrate, Methanol, Validation, ICH, Pharmaceutical Analysis},
        month = {April},
        }

Cite This Article

NARSALE, V. V., & bhosale, R., & kukade, V., & baokar, S. (2026). OPTIMIZATION AND VALIDATION OF UV ANALYTICAL METHODS FOR FENOFIBRATE USING VARIOUS CALIBRATION TECHNIQUES. International Journal of Innovative Research in Technology (IJIRT), 12(11), 11158–11164.

Related Articles