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@article{199602,
        author = {Atharva Manish Tiwari and Nachiket Sham Thenge and Sakshi Sopan Tribhuwan and Aniket Raosaheb Tathe and Preeti More},
        title = {FORMULATION AND EVALUATION OF POLYHERBAL ANTI-ACNE CREAM CONTAINING AZADIRACHTA INDICA, OCIMUM SANCTUM, AND ALOE VERA},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {11},
        pages = {14582-14588},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=199602},
        abstract = {Acne vulgaris is a multifactorial dermatological disorder characterized by inflammation, microbial colonization, and excessive sebum production. Conventional therapies often result in side effects and microbial resistance, necessitating the development of safer alternatives. The present study focuses on the formulation and evaluation of a polyherbal anti-acne cream containing Azadirachta indica (Neem), Ocimum sanctum (Tulsi), and Aloe vera. Herbal extracts were prepared using hydro-alcoholic maceration and incorporated into an oil-in-water (O/W) emulsion base using a stearic acid–triethanolamine system. The formulation was evaluated for physicochemical parameters including pH, spreadability, homogeneity, and stability. The prepared cream exhibited acceptable characteristics and is expected to demonstrate antimicrobial and anti-inflammatory activity due to the synergistic action of herbal constituents. This study highlights the potential of herbal formulations as effective and safe alternatives for acne management.},
        keywords = {},
        month = {April},
        }