FORMULATION AND EVALUATION OF TENELIGLIPTINE LOADED PRONIOSOMAL GEL FOR TRANSDERMAL DELIVERY

  • Unique Paper ID: 199932
  • Volume: 12
  • Issue: 12
  • PageNo: 772-776
  • Abstract:
  • Teneligliptin is widely used in the treatment of Type 2 Diabetes Mellitus, but its oral administration has certain limitations. This study focuses on the formulation and evaluation of a Teneligliptin-loaded proniosomal gel for improved transdermal delivery. Proniosomal gels were prepared using non-ionic surfactants and evaluated for entrapment efficiency, vesicle size, pH, viscosity, and in vitro drug release. The optimized formulation showed good physicochemical properties with sustained drug release. The results suggest that the developed proniosomal gel could serve as a promising alternative to conventional delivery systems for enhanced therapeutic effectiveness and patient compliance.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{199932,
        author = {Aishwarya v shinde and Vrushali Suryawanshi and Yogita Bhingole and Aruna Kakad},
        title = {FORMULATION AND EVALUATION OF TENELIGLIPTINE LOADED PRONIOSOMAL GEL FOR TRANSDERMAL DELIVERY},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {12},
        pages = {772-776},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=199932},
        abstract = {Teneligliptin is widely used in the treatment of Type 2 Diabetes Mellitus, but its oral administration has certain limitations. This study focuses on the formulation and evaluation of a Teneligliptin-loaded proniosomal gel for improved transdermal delivery. Proniosomal gels were prepared using non-ionic surfactants and evaluated for entrapment efficiency, vesicle size, pH, viscosity, and in vitro drug release. The optimized formulation showed good physicochemical properties with sustained drug release. The results suggest that the developed proniosomal gel could serve as a promising alternative to conventional delivery systems for enhanced therapeutic effectiveness and patient compliance.},
        keywords = {Teneligliptin, Type 2 Diabetes Mellitus, Proniosomal gel, Transdermal drug delivery, Entrapment efficiency In vitro drug release Controlled release non-ionic surfactants},
        month = {May},
        }

Cite This Article

shinde, A. V., & Suryawanshi, V., & Bhingole, Y., & Kakad, A. (2026). FORMULATION AND EVALUATION OF TENELIGLIPTINE LOADED PRONIOSOMAL GEL FOR TRANSDERMAL DELIVERY. International Journal of Innovative Research in Technology (IJIRT), 12(12), 772–776.

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