Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
@article{200968,
author = {Pankaj Gajanan Navghare and Nagesh Ramesh Mohrut and Pratik Kailas Awasarmol and Vanita Kadu Bharsakle and Rupali Gajanan Pimple},
title = {A REVIEW ARTICLE ON COMPARATIVE STUDY OF GENERIC AND BRANDED TELMISARTAN TABLET},
journal = {International Journal of Innovative Research in Technology},
year = {2026},
volume = {12},
number = {12},
pages = {2487-2492},
issn = {2349-6002},
url = {https://ijirt.org/article?manuscript=200968},
abstract = {Generic medications have been shown to be therapeutically equivalent to their branded counterparts through in-vitro comparative studies. This means that they contain identical quantities of the active ingredient and produce comparable clinical effects in patients. To assess the quality of generic and branded tablets of a particular medication, we employed in-vitro methods. A series of in-vitro tests, including general appearance, thickness, diameter, hardness, friability, weight variation, content uniformity, disintegration, and dissolution tests, were performed on both generic and branded tablets of the same medication. Three of them having a relatively huge number of impurities compared to the brand. The other six generics showed more or less the same mean drug content, dissolution rate as that of the brand and a better solubility. Three generics showed to have a comparable number and number of impurities as that of the brand. The dissolution profiles of four generics were comparable to that of the brand in two different dissolution media out of the four media used in the dissolution tests. This study showed that while some generics may be of inferior quality to that of their brand counterparts, others can be of approximately the same quality as that of the brand. the objective of this overview was to find out the tolerable. Deviations between generic and brand name drugs which should not alter the pharmacology. Using inactive additives in the generic drug different than in the brand name drug, such as binders, glidants, diluents, anti-adherents, disintegrants or polymer carrier material and filler should not change the drug bioavailability and pharmacokinetic parameters as long as both products using the identical active ingredient(s) in equivalent amounts. Even if both drug products are bioequivalent to each other in terms of active ingredient, they are not in terms of inactive ingredients. Hence, the probability of unexpected adverse drug reaction and allergies from the generic formulation are possible, especially, when people react sensitive toward specific component.},
keywords = {Generic, Branded, Telmisartan},
month = {May},
}
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