Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
@article{201562,
author = {Aayesha Mustaffa Shaikh and Taher Abedin Jigar and Tausif Sajid Shaikh},
title = {FORMULATION AND EVALUATION OF HERBAL ANTI-ECZEMA GEL CONTAINING GLYCYRRHIZA GLABRA EXTRACT},
journal = {International Journal of Innovative Research in Technology},
year = {2026},
volume = {12},
number = {12},
pages = {4198-4201},
issn = {2349-6002},
url = {https://ijirt.org/article?manuscript=201562},
abstract = {Objective of the study was formulation and evaluation of an anti-eczema gel using extract of Glycyrrhiza glabra (Liquorice). Increasing use of herbal drugs is associated with their ability to provide therapeutic benefits with better patient compliance, which makes these agents an important alternative to traditional treatments. The current study involved preparation of a topical gel formulation with the help of Carbopol 940 as the gelling agent and other required excipients, including propylene glycol, glycerin, methyl paraben, propyl paraben, disodium EDTA, and triethanolamine.
The formulated gel was subjected to various physicochemical evaluations involving parameters such as appearance, homogeneity, pH, viscosity, spread ability, and skin irritation tests. Apart from formulation development, pre-formulation studies including organoleptic evaluation, solubility, UV visible spectrophotometry, and FTIR analysis were conducted to identify the nature and compatibility of the active ingredient. Results revealed the presence of satisfactory properties such as uniform composition, adequate viscosity, smoothness, and spread ability of the gel. Furthermore, the tested gel formulation proved to be compatible with skin pH and free from skin irritation.
Conclusively, the anti-eczema gel with the herbal active ingredient Glycyrrhiza glabra extract demonstrated excellent physicochemical properties, which made it a promising herbal topical formulation for eczema.},
keywords = {Glycyrrhiza glabra, Anti-eczema gel, Carbopol 940, Topical formulation, Herbal preparation.},
month = {May},
}
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