High-Sensitivity Screening: Evaluating Triage Specificity Overloads and Overtreatment Risks in Primary HPV and Self-Sampling Paradigms

  • Unique Paper ID: 203924
  • Volume: 13
  • Issue: 1
  • PageNo: 1189-1195
  • Abstract:
  • Although the movement towards HPV DNA screening and patient-administered self-sampling has led to enhanced coverage and sensitivity, the secondary public health issue that arises is triage overload. Transient HPV infections, which tend to resolve on their own without treatment, are being picked up like never before. The downstream effects in infrastructures where resources are limited are massive; positive cases overwhelm colposcopy facilities, making screening economically inefficient and mentally stressful for unnecessary over treatment. This research seeks to illustrate the challenges associated with the specificity of primary tests. The findings of our study reveal that without high specificity during the triage process, increased sensitivity will destabilize the entire process.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{203924,
        author = {Zubin Savla and Dr. Asha Durafe and Dr. Manisha Mane},
        title = {High-Sensitivity Screening: Evaluating Triage Specificity Overloads and Overtreatment Risks in Primary HPV and Self-Sampling Paradigms},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {13},
        number = {1},
        pages = {1189-1195},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=203924},
        abstract = {Although the movement towards HPV DNA screening and patient-administered self-sampling has led to enhanced coverage and sensitivity, the secondary public health issue that arises is triage overload. Transient HPV infections, which tend to resolve on their own without treatment, are being picked up like never before. The downstream effects in infrastructures where resources are limited are massive; positive cases overwhelm colposcopy facilities, making screening economically inefficient and mentally stressful for unnecessary over treatment. This research seeks to illustrate the challenges associated with the specificity of primary tests. The findings of our study reveal that without high specificity during the triage process, increased sensitivity will destabilize the entire process.},
        keywords = {Cervical Cancer, Primary HPV Testing, Self-Sampling, Over treatment, Resource Allocation.},
        month = {June},
        }

Cite This Article

Savla, Z., & Durafe, D. A., & Mane, D. M. (2026). High-Sensitivity Screening: Evaluating Triage Specificity Overloads and Overtreatment Risks in Primary HPV and Self-Sampling Paradigms. International Journal of Innovative Research in Technology (IJIRT), 13(1), 1189–1195.

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