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@article{204155,
        author = {Ankush Bharath and Dhruv Goyal and Dr. Rajveer Singh and Dr. Dinesh Upadhyay and Dr. Shubhranshu Panda},
        title = {Narco Analysis agents:Truth Serum’s properties for Psychotherapeutic activity},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {13},
        number = {1},
        pages = {1771-1778},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=204155},
        abstract = {This paper presents a comprehensive medical analysis evaluating the evolution of historical forensic "truth serums" into targeted tools in modern psychiatric healing and neurobiology. The study systematically analyzes the pharmacokinetic and multi-receptor pharmacodynamic profiles of thiopental sodium, scopolamine hydrobromide, and propofol. At controlled concentrations, these agents induce central nervous system (CNS) disinhibition by suppressing high-level cortical executive functions, facilitating cathartic abreaction in chronic Post-Traumatic Stress Disorder (PTSD) and showing rapid-acting antidepressant efficacy. However, a critical neurobiological paradox is established regarding acute trauma management: the administration of propofol during the immediate aftermath of trauma may pathologically consolidate subcortical fear memory traces in the amygdala, potentially increasing the subsequent incidence of postoperative PTSD (10). This paper outlines clinical profiles and safety considerations regarding the use of these agents in psychiatric care.},
        keywords = {Acute trauma, Amygdala, CNS disinhibition, Narcoanalysis, Post-Traumatic Stress Disorder, Propofol, Scopolamine, Thiopental sodium.},
        month = {June},
        }