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@article{204570,
        author = {Shrimant V. Bidarkote},
        title = {Recent Advances in Analytical Method Development for Combination Antidiabetic and Cardiovascular Drugs- Review},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {13},
        number = {1},
        pages = {2983-2988},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=204570},
        abstract = {The increasing prevalence of diabetes mellitus and cardiovascular diseases has led to the extensive use of combination therapies involving antidiabetic and cardiovascular agents. Accurate and reliable analytical methods are essential for quality control, stability assessment, and regulatory compliance of these pharmaceutical formulations. Among the available analytical techniques, ultraviolet (UV) spectrophotometry and reverse-phase high-performance liquid chromatography (RP-HPLC) are widely employed due to their simplicity, sensitivity, accuracy, and reproducibility. UV spectrophotometric methods offer cost-effective and rapid analysis, whereas RP-HPLC provides superior selectivity and precise separation of multiple active pharmaceutical ingredients. This review summarizes the analytical approaches used for the simultaneous determination of antidiabetic and cardiovascular agents in bulk drugs and pharmaceutical formulations. Emphasis is placed on method development strategies, chromatographic optimization, validation requirements according to ICH guidelines, and recent advancements in pharmaceutical analysis. The review highlights the importance of robust and validated analytical methods in ensuring pharmaceutical product quality, safety, efficacy, and regulatory acceptance.},
        keywords = {Antidiabetic Agents, Cardiovascular Agents, UV Spectrophotometry, RP-HPLC, Method Validation},
        month = {June},
        }