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@article{204710,
        author = {Miss. Anushri Govind Shinde and Prof. Sudhir S. Koushik and Mr. Kishan A. Kukar},
        title = {Formulation and Evaluation of an Herbal Wound Healing Gel Containing Mussaenda erythrophylla Leaf Extract},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {13},
        number = {1},
        pages = {3273-3284},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=204710},
        abstract = {The present study entitled “Formulation and Evaluation of Wound Healing Gel Containing Mussaenda erythrophylla Leaves Extract” was undertaken with the aim of developing a safe, effective, and stable herbal topical formulation for wound healing applications. Leaves of Mussaenda erythrophylla were collected from SRTMU campus, Nanded, and authenticated at Science College, Nanded, by Dr. Marathe. The collected plant material was shade dried, powdered, and subjected to extraction using a suitable solvent system. The obtained extract was evaluated for phytochemical constituents, confirming the presence of flavonoids, tannins, and phenolic compounds, which are known to contribute to wound healing activity. The extract was further characterized using FTIR spectroscopy to identify functional groups and confirm the presence of bioactive compounds. Based on preliminary studies, five gel formulations (HG1–HG5) were prepared using appropriate gelling agents and varying concentrations of the plant extract. All prepared formulations were evaluated for physicochemical parameters including physical appearance, homogeneity, pH, viscosity, spreadability, drug content, and washability. The formulations exhibited satisfactory organoleptic properties with smooth texture and good consistency. The pH of all batches ranged between 6.05 and 6.24, which is suitable for topical application. Viscosity values indicated good gel strength, while spreadability ensured ease of application. Drug content analysis confirmed uniform distribution of the extract in all formulations. Among all batches, formulation HG3 was identified as the optimized formulation due to its superior characteristics, including optimal pH (6.18), highest viscosity, maximum spreadability, and highest drug content (99.4%). The formulation also showed excellent homogeneity and washability. The optimized batch (HG3) was subjected to accelerated stability studies, which indicated no significant changes in physical appearance, pH, viscosity, spreadability, and drug content over a period of six months, confirming the stability of the formulation. In conclusion, the developed herbal gel containing Mussaenda erythrophylla leaves extract demonstrated satisfactory physicochemical properties and stability, indicating its potential as an effective wound healing agent. The study supports the use of plant-based formulations as a promising alternative to conventional synthetic products.},
        keywords = {Mussaenda erythrophylla, wound healing, herbal gel, topical formulation, phytochemical screening, FTIR, viscosity, spreadability, stability studies},
        month = {June},
        }