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@article{204898,
        author = {Manish Kumar and Anita Singh and Neeku Singh and Aman Kumar and Annasa Kundu and Deepak Joshi and Ajeet Kumar},
        title = {Isatin Derivatives and Their Pharmacological Potential: Conventional and Green Synthesis Methods},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {13},
        number = {1},
        pages = {5668-5684},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=204898},
        abstract = {Isatin is an eight-carbon containing nitrogenous compound which is available in nature. It is a multifused cyclic compound which is made upon fusion of Six-membered cyclic and Five-membered cyclic ring. Earlier it was discovered by the Erdmann and Laurent in 1964. Before the discovery in nature.It’s IUPAC Name: 1-H-indol-2,3-dione .It is also known as Tribulin .The isatin scaffold shows the numerous of chemical reaction such as, N-halogenation, Alkylation, Acylation, N-substitution & such type of naming reaction (Sandmeyer, Clasein etc).It shows biological and pharmacological effect such as- cardioprotective, anti-diabetic, CNS depressant, anti-inflammatory, anti-cancer, anti-microbial etc.It is widely assign and disburse in group of cells and body fluid major  intracellular fluid.Isatin is effective in alpha-amylase, Dipeptidyl Peptidase 4  (DPP4), alpha-glucosidase, COX enzyme.},
        keywords = {IUPAC, Anti-diabetic Anti-inflammatory, Scaffold, DPP4, COX},
        month = {June},
        }