FORMULATION AND EVALUATION OF ANTIDIABETIC HERBAL TABLET

  • Unique Paper ID: 205232
  • Volume: 13
  • Issue: 1
  • PageNo: 5581-5587
  • Abstract:
  • Diabetes mellitus is a rapidly escalating global metabolic disorder characterized by absolute or relative insulin deficiency, leading to chronic hyperglycemia. While synthetic antidiabetic agents effectively manage blood glucose, their long-term use is frequently limited by high financial cost, drug resistance, and systemic side effects. Consequently, herbal drug delivery systems utilizing biocompatible phytomedicines are gaining significant traction to optimize therapeutic efficacy and enhance patient compliance. Moringa oleifera represents a highly effective, multi-target botanical intervention for diabetes management. Standardizing its drying and processing protocols ensures a stable, nutrient-dense profile that mitigates synthetic side effects, presenting a viable foundation for advanced, sustained- release herbal drug formulations. Moringa oleifera leaves naturally contain exceptionally high concentrations of non-heme iron. In healthy individuals, this is a major nutritional benefit. However, in diabetic patients, excess iron accumulation can act as a catalyst for the Fenton Reaction, accelerating hydroxyl free radical production and exacerbating macrovascular tissue damage.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{205232,
        author = {Amruta Subhash Bhange and Ogar Bhalaram Choudhary and Assoc.Prof. Vaibhav Narwade and Dr. Vijaykumar Kale and Dr. Mahesh Thakare},
        title = {FORMULATION AND EVALUATION OF ANTIDIABETIC HERBAL TABLET},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {13},
        number = {1},
        pages = {5581-5587},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=205232},
        abstract = {Diabetes mellitus is a rapidly escalating global metabolic disorder characterized by absolute or relative insulin deficiency, leading to chronic hyperglycemia. While synthetic antidiabetic agents effectively manage blood glucose, their long-term use is frequently limited by high financial cost, drug resistance, and systemic side effects. Consequently, herbal drug delivery systems utilizing biocompatible phytomedicines are gaining significant traction to optimize therapeutic efficacy and enhance patient compliance. Moringa oleifera represents a highly effective, multi-target botanical intervention for diabetes management. Standardizing its drying and processing protocols ensures a stable, nutrient-dense profile that mitigates synthetic side effects, presenting a viable foundation for advanced, sustained- release herbal drug formulations. Moringa oleifera leaves naturally contain exceptionally high concentrations of non-heme iron. In healthy individuals, this is a major nutritional benefit. However, in diabetic patients, excess iron accumulation can act as a catalyst for the Fenton Reaction, accelerating hydroxyl free radical production and exacerbating macrovascular tissue damage.},
        keywords = {Moringa oleifera, Diabetes Mellitus, Flavonoids, AGE-RAGE Axis, Herbal Drug Delivery, Phytomedicine.},
        month = {June},
        }

Cite This Article

Bhange, A. S., & Choudhary, O. B., & Narwade, A. V., & Kale, D. V., & Thakare, D. M. (2026). FORMULATION AND EVALUATION OF ANTIDIABETIC HERBAL TABLET. International Journal of Innovative Research in Technology (IJIRT), 13(1), 5581–5587.

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