GC-MS Analysis of Phyto-components from the Leaves of Achyranthes aspera L. of Ranchi, Jharkhand used against Skin Diseases

  • Unique Paper ID: 205304
  • Volume: 13
  • Issue: 1
  • PageNo: 7439-7444
  • Abstract:
  • The escalating rate of drug-resistant dermatological conditions demands the exploration of plant-derived alternatives. This study evaluates the lipophilic chemotype of Achyranthes aspera L. leaves from Ranchi, Jharkhand, validating its empirical use against skin diseases. Cold ethanolic maceration followed by Gas Chromatography-Mass Spectrometry (GC-MS) analysis revealed 17 distinct phyto-components over a 35-minute runtime. Hexadecanoic acid, methyl ester emerged as the predominant fraction (29.60), followed by methyl oleate (18.80), phytol (8.85), and methyl stearate (6.68). The presence of these fatty acid esters, along with bioactive tissue-repair agents like squalene (5.30) and lupeol (1.91), establishes a strong biochemical foundation for the plant’s anti-inflammatory, antimicrobial, and barrier-recovery properties in ethno-dermatology.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{205304,
        author = {Vikram Kumar Sharma and Rashmi Mishra, Assistant Professor, Department of Botany, Dr. Shyama Prasad Mukherjee University, Ranchi, Jharkhand, India},
        title = {GC-MS Analysis of Phyto-components from the Leaves of Achyranthes aspera L. of Ranchi, Jharkhand used against Skin Diseases},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {13},
        number = {1},
        pages = {7439-7444},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=205304},
        abstract = {The escalating rate of drug-resistant dermatological conditions demands the exploration of plant-derived alternatives. This study evaluates the lipophilic chemotype of Achyranthes aspera L. leaves from Ranchi, Jharkhand, validating its empirical use against skin diseases. Cold ethanolic maceration followed by Gas Chromatography-Mass Spectrometry (GC-MS) analysis revealed 17 distinct phyto-components over a 35-minute runtime. Hexadecanoic acid, methyl ester emerged as the predominant fraction (29.60), followed by methyl oleate (18.80), phytol (8.85), and methyl stearate (6.68). The presence of these fatty acid esters, along with bioactive tissue-repair agents like squalene (5.30) and lupeol (1.91), establishes a strong biochemical foundation for the plant’s anti-inflammatory, antimicrobial, and barrier-recovery properties in ethno-dermatology.},
        keywords = {Achyranthes aspera L., GC-MS analysis, Phyto-components, Ranchi (Jharkhand), Skin diseases, Bioactive fatty acids.},
        month = {June},
        }

Cite This Article

Sharma, V. K., & India, R. M. A. P. D. O. B. D. S. P. M. U. R. J. (2026). GC-MS Analysis of Phyto-components from the Leaves of Achyranthes aspera L. of Ranchi, Jharkhand used against Skin Diseases. International Journal of Innovative Research in Technology (IJIRT), 13(1), 7439–7444.

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