Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
@article{205580,
author = {Sayyam Tarey},
title = {ROLE OF OLIVE OIL IN SKIN HEALTH AND TOPICAL DRUG DELIVERY: A REVIEW},
journal = {International Journal of Innovative Research in Technology},
year = {2026},
volume = {13},
number = {1},
pages = {7092-7095},
issn = {2349-6002},
url = {https://ijirt.org/article?manuscript=205580},
abstract = {Olive oil has gained considerable attention in the pharmaceutical, cosmetic, and dermatological fields due to its multifunctional role in promoting skin health and enhancing topical drug delivery. Derived from the fruits of the olive tree (Olea europaea L.), olive oil is rich in monounsaturated fatty acids, particularly oleic acid, along with numerous bioactive compounds such as polyphenols, flavonoids, tocopherols, squalene, carotenoids, and phytosterols. These constituents contribute to its wide range of biological activities, including antioxidant, anti-inflammatory, antimicrobial, moisturizing, and wound-healing effects (2). The antioxidant components of olive oil help protect the skin against oxidative stress caused by environmental pollutants and ultraviolet radiation, thereby reducing premature skin aging and cellular damage. Its emollient and moisturizing properties assist in maintaining skin hydration, improving elasticity, and strengthening the skin barrier, making it beneficial for the management of various dermatological conditions such as eczema, psoriasis, dermatitis, and dry skin disorders (5).
In addition to its therapeutic effects on skin health, olive oil plays a significant role in topical and transdermal drug delivery systems. The high concentration of oleic acid acts as a natural permeation enhancer by disrupting the tightly packed lipid structure of the stratum corneum, thereby facilitating improved penetration of active pharmaceutical ingredients through the skin. Olive oil also serves as an effective carrier for lipophilic drugs, enhancing their solubility, stability, and bioavailability. Its compatibility with a wide variety of excipients has led to its incorporation into numerous dosage forms, including creams, ointments, lotions, gels, emulsions, nanoemulsions, microemulsions, liposomes, solid lipid nanoparticles, and nanostructured lipid carriers. These advanced delivery systems offer advantages such as controlled drug release, targeted delivery, increased skin retention, and improved therapeutic efficacy (11).},
keywords = {},
month = {June},
}
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