NANOFORMULATIONS OF MORINGA OLEIFERA PHYTOCONSTITUENTS: CURRENT ADVANCES AND FUTURE PROSPECTS

  • Unique Paper ID: 206109
  • Volume: 13
  • Issue: 2
  • PageNo: 1618-1632
  • Abstract:
  • Moringa oleifera Lam. is a nutritionally and pharmacologically important medicinal plant widely recognized for its diverse therapeutic potential. Different parts of the plant, including leaves, seeds, flowers, pods, bark, and roots, contain numerous bioactive phytoconstituents such as flavonoids, phenolic acids, glucosinolates, alkaloids, tannins, saponins, carotenoids, vitamins, and minerals. These compounds possess antioxidant, anti-inflammatory, antimicrobial, antidiabetic, anticancer, hepatoprotective, cardioprotective, neuroprotective, and wound-healing properties. However, their clinical application is often restricted by poor aqueous solubility, low bioavailability, rapid metabolism, and chemical instability. Nanotechnology-based drug delivery systems have emerged as effective approaches to overcome these limitations by enhancing solubility, protecting phytochemicals from degradation, improving absorption, enabling controlled release, and facilitating targeted delivery. Various nanoformulations, including polymeric nanoparticles, liposomes, phytosomes, nanoemulsions, solid lipid nanoparticles, nanostructured lipid carriers, nanogels, dendrimers, and green-synthesized metallic nanoparticles, have demonstrated improved therapeutic performance of M. oleifera phytoconstituents. This review summarizes the phytochemical composition, nanoformulation strategies, therapeutic applications, recent advances, current challenges, and future prospects of nano-enabled M. oleifera, highlighting its potential for developing effective pharmaceutical and nutraceutical products.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{206109,
        author = {Ruchira P. Kambire and Kiran S. Gaikwad and Diksha C. Mhatre and Sneha D. Bansode and Saloni S. Sapkal},
        title = {NANOFORMULATIONS OF MORINGA OLEIFERA PHYTOCONSTITUENTS: CURRENT ADVANCES AND FUTURE PROSPECTS},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {13},
        number = {2},
        pages = {1618-1632},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=206109},
        abstract = {Moringa oleifera Lam. is a nutritionally and pharmacologically important medicinal plant widely recognized for its diverse therapeutic potential. Different parts of the plant, including leaves, seeds, flowers, pods, bark, and roots, contain numerous bioactive phytoconstituents such as flavonoids, phenolic acids, glucosinolates, alkaloids, tannins, saponins, carotenoids, vitamins, and minerals. These compounds possess antioxidant, anti-inflammatory, antimicrobial, antidiabetic, anticancer, hepatoprotective, cardioprotective, neuroprotective, and wound-healing properties. However, their clinical application is often restricted by poor aqueous solubility, low bioavailability, rapid metabolism, and chemical instability. Nanotechnology-based drug delivery systems have emerged as effective approaches to overcome these limitations by enhancing solubility, protecting phytochemicals from degradation, improving absorption, enabling controlled release, and facilitating targeted delivery. Various nanoformulations, including polymeric nanoparticles, liposomes, phytosomes, nanoemulsions, solid lipid nanoparticles, nanostructured lipid carriers, nanogels, dendrimers, and green-synthesized metallic nanoparticles, have demonstrated improved therapeutic performance of M. oleifera phytoconstituents. This review summarizes the phytochemical composition, nanoformulation strategies, therapeutic applications, recent advances, current challenges, and future prospects of nano-enabled M. oleifera, highlighting its potential for developing effective pharmaceutical and nutraceutical products.},
        keywords = {Moringa oleifera; Nanotechnology; Nanoformulations; Phytoconstituents; Polymeric nanoparticles; Liposomes; Nanoemulsion; Drug delivery; Herbal therapeutics; Bioavailability.},
        month = {July},
        }

Cite This Article

Kambire, R. P., & Gaikwad, K. S., & Mhatre, D. C., & Bansode, S. D., & Sapkal, S. S. (2026). NANOFORMULATIONS OF MORINGA OLEIFERA PHYTOCONSTITUENTS: CURRENT ADVANCES AND FUTURE PROSPECTS. International Journal of Innovative Research in Technology (IJIRT), 13(2), 1618–1632.

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