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@article{206244,
        author = {Kawde Samiksha Prakash and Dr. A. D. Kshirsagar and S. M. Ambore},
        title = {Development and evaluation of antioxidant and anti-inflammatory tablets from swietenia macrophylla leaves"},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {13},
        number = {2},
        pages = {598-609},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=206244},
        abstract = {This study concentrated on the development and assessment of herbal tablets created from Swietenia macrophylla leaf extract for their antioxidant and anti-inflammatory properties. Herbal remedies are commonly utilized today because they are viewed as safer, more affordable, and result in fewer adverse effects compared to synthetic drugs. The leaves of Swietenia macrophylla possess significant phytochemicals including flavonoids, phenolic compounds, tannins, alkaloids, and limonoids, recognized for their antioxidant and anti-inflammatory effects. Fresh leaves of Swietenia macrophylla were gathered, verified, dried in the shade, and ground into powder. The tablets were formulated using the wet granulation technique with appropriate excipients such as lactose, starch, microcrystalline cellulose, talc, and magnesium stearate. Prior to compression, the granules were assessed for pre-formulation metrics such as bulk density, tapped density, angle of repose, Carr’s index, and Hausner’s ratio to determine their flow characteristics and compressibility. The manufactured tablets underwent additional assessment for a range of quality control metrics including physical appearance, weight variation, hardness, friability, thickness, disintegration time, dissolution, and content uniformity. The findings indicated that all formulations had satisfactory physicochemical characteristics within official standards. The tablets displayed excellent hardness, minimal friability, consistent thickness, acceptable weight variation, and adequate disintegration time. Among all the formulation, batch F4 demonstrated superior hardness and an acceptable dissolution profile in comparison to the other batches. The research determined that leaf extract from Swietenia macrophylla can be effectively developed into stable herbal tablets that possess notable antioxidant and anti-inflammatory properties Consequently, the formulated herbal remedy could serve as an effective natural option for addressing oxidative stress and inflammatory issues, offering enhanced patient adherence and inflammatory issues, offering enhanced patient adherence and reduced side effects.},
        keywords = {},
        month = {July},
        }