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@article{207091,
        author = {Maithili shinde and Shrikant S Magdum and Vedhashree G shinde and Pranali Mahadev Bhosale and Arati Ajit Patil and Nujahat m.husen sanadi},
        title = {Smart 3D-Printed Drug-Loaded Scaffolds for Skin Tissue Regeneration: Biomaterials, Fabrication Strategies, Therapeutic Applications, and Future Perspectives},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {13},
        number = {2},
        pages = {4039-4054},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=207091},
        abstract = {Three-dimensional (3D) printing has become an advanced biofabrication approach for designing personalized scaffolds that combine structural support with controlled drug delivery for skin tissue regeneration. Traditional wound dressings mainly provide protection but have limited ability to overcome challenges such as inflammation, infection, poor vascularization, and delayed tissue repair. This review highlights recent progress (2021–2026) in smart 3D-printed drug-loaded scaffolds, focusing on biomaterials, printing technologies, therapeutic incorporation, and responsive drug delivery systems. Different fabrication methods, including extrusion printing, stereolithography, and fused deposition modeling, are discussed with emphasis on their advantages and applications in regenerative medicine. The role of natural, synthetic, and composite biomaterials in improving scaffold strength, biodegradation, and cellular interaction is explored. Emerging smart scaffolds responsive to biological stimuli, along with the integration of antibiotics, growth factors, and nanotherapeutics, are evaluated for enhanced wound healing. Future perspectives include AI-based design, 4D printing, biosensor integration, and personalized regenerative therapies.},
        keywords = {3D printing; Smart scaffolds; Drug delivery; Skin tissue regeneration; Wound healing; Biomaterials; Bioprinting; Regenerative medicine.},
        month = {July},
        }