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@article{207563,
        author = {Dr.G. Gomathy and Raksha sree .v},
        title = {EXTRACTION OF CHITOSAN WASTE NANOPARTICLES FROM PRAWN SHELL WASTE AND EVALUATION OF ANTI INFLAMMATORY ACTIVITY},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {13},
        number = {3},
        pages = {1700-1705},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=207563},
        abstract = {Inflammation is a protective biological response against tissue injury and infection however, prolonged or uncontrolled inflammation is associated with various chronic diseases such as arthritis, cardiovascular disorders, and cancer.Chitosan, a biopolymer obtained from crustacean shell waste, has gained considerable attention due to its biodegradability, biocompatibility, and notable biological properties, including antiinflammatory activity. The present study aimed to extract chitosan from prawn shell waste, synthesize chitosan-based nanoparticles, and evaluate their in-vitro anti-inflammatory potential. Prawn shell waste was processed and subjected to alkaline deacetylation to obtain purified chitosan. Chitosan nanoparticles were synthesized using the ionic gelation method with sodium tripolyphosphate as a cross-linking agent, a widely reported and efficient technique for nanoparticle preparation. The formation of nanoparticles was confirmed by UV–Visible spectrophotometric analysis. The in-vitro anti-inflammatory activity of the synthesized chitosan nanoparticles was evaluated using the lipoxygenase (LOX) inhibition assay, as lipoxygenase plays a key role in inflammatory mediator synthesis. The study concludes that prawn shell–derived chitosan nanoparticles can serve as a promising, eco-friendly, and biocompatible natural anti-inflammatory agent, while also promoting the sustainable utilization of marine .},
        keywords = {Prawn shell, Chitosan, Lipoxygenase, Nanoparticles .},
        month = {August},
        }