Invitro antimicrobial and biocompatible properties of sulphated glycosaminoglycans extracted from the skin of puffer fish Lagocephalus inermis

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ISSN: 2349-6002 ESTD Year: 2014

UGC approved journal no 47859

Invitro antimicrobial and biocompatible properties of sulphated glycosaminoglycans extracted from the skin of puffer fish Lagocephalus inermis
Author(s):
Iswariya . S, Dr. S.Shanmugam
Keywords:
Antimicrobial activity, Fish skin, Glycosaminoglycans, Puffer fish.
Abstract
The present work was conducted to study the biocompatibility and antimicrobial activity of the glycosaminoglycans (GAGs) extracted from the skin of underutilized puffer fish Lagocephalus inermis. The extracted GAGs showed potent antimicrobial activity against all the tested microorganisms such as Escherichia coli, Staphylococcus aureus, Klebsiella pneumonia, Bacillus subtilis and Pseudomonas aeruginosa. The extracted GAGs was also evaluated using NIH3T3 fibroblast cell lines for its biocompatibility. The result suggested that the polysaccharide extracted from the non-edible fish skin was converted to a economically valuable product which will fulfill the emerging needs for the bioactive metabolites in various pharmaceutical applications and also prevents the overexploitation of other endangered species.
Article Details
Unique Paper ID: 150811 Publication Volume & Issue: Volume 7, Issue 10 Page(s): 66 - 70
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