Invitro antimicrobial and biocompatible properties of sulphated glycosaminoglycans extracted from the skin of puffer fish Lagocephalus inermis

  • Unique Paper ID: 150811
  • Volume: 7
  • Issue: 10
  • PageNo: 66-70
  • Abstract:
  • The present work was conducted to study the biocompatibility and antimicrobial activity of the glycosaminoglycans (GAGs) extracted from the skin of underutilized puffer fish Lagocephalus inermis. The extracted GAGs showed potent antimicrobial activity against all the tested microorganisms such as Escherichia coli, Staphylococcus aureus, Klebsiella pneumonia, Bacillus subtilis and Pseudomonas aeruginosa. The extracted GAGs was also evaluated using NIH3T3 fibroblast cell lines for its biocompatibility. The result suggested that the polysaccharide extracted from the non-edible fish skin was converted to a economically valuable product which will fulfill the emerging needs for the bioactive metabolites in various pharmaceutical applications and also prevents the overexploitation of other endangered species.

Copyright & License

Copyright © 2025 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{150811,
        author = {Iswariya . S and Dr. S.Shanmugam},
        title = {Invitro antimicrobial and biocompatible properties of sulphated glycosaminoglycans extracted from the skin of puffer fish Lagocephalus inermis},
        journal = {International Journal of Innovative Research in Technology},
        year = {},
        volume = {7},
        number = {10},
        pages = {66-70},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=150811},
        abstract = {The present work was conducted to study the biocompatibility and antimicrobial activity of the glycosaminoglycans (GAGs) extracted from the skin of underutilized puffer fish Lagocephalus inermis. The extracted GAGs showed potent antimicrobial activity against all the tested microorganisms such as Escherichia coli, Staphylococcus aureus, Klebsiella pneumonia, Bacillus subtilis and Pseudomonas aeruginosa. The extracted GAGs was also evaluated using NIH3T3 fibroblast cell lines for its biocompatibility. The result suggested that the polysaccharide extracted from the non-edible fish skin was converted to a economically valuable product which will fulfill the emerging needs for the bioactive metabolites in various pharmaceutical applications and also prevents the overexploitation of other endangered species. },
        keywords = {Antimicrobial activity, Fish skin, Glycosaminoglycans, Puffer fish.},
        month = {},
        }

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