Author Login IJIRT Partner Network (IPN) Login

Clinical Effectiveness of PET/CT, PET, CT and MRI for Breast, Cervical, Head and Neck, Gastric and Lung Cancer-A Systematic Review and Meta-analysis

  • Unique Paper ID: 150825
  • Volume: 7
  • Issue: 10
  • PageNo: 89-99
  • Abstract:
  • Back ground: We performed a systematic review and meta-analysis to assess the accuracy of PET/CT, PET, CT and MRI for the detection of Breast cancer, Cervical cancer, Head and Neck cancer, Gastric cancer and Lung Cancer. Methods: Electronic databases were searched for studies assessing the sensitivity and specificity of PET/CT, PET, CT and MRI. A total of 345 articles from 61 meta- analysis and 3 HTA’s were included in this review. Revman software was used to assess the sensitivity, specificity. The Quality Assessment of Diagnostic Accuracy Studies 2 (QUADAS-2). Results: Total number of studies included in this systematic review and meta-analysis are 345 studies comprising of patients with Cervical cancer, Breast cancer, Head and Neck cancer, Gastric cancer and Lung cancer. The pooled sensitivity and specificity estimate of PET/CT, PET, CT and MRI for detecting above mentioned five cancers. After pooling all studies of CT, MRI, PET and PET/CT for cervical cancer the Forest plot of sensitivity and specificity of CT 0.62 (0.57, 0.67), 0.92 (0.57, 0.67), MRI 0.52 (0.49,0.55), 0.96 (0.95, 0.96) PET 0.90 (0.86,0.93) 0.93(0.91, 0.94) and PET/CT 0.65(0.62, 0.68) 0.97(0.97,0.98) in detecting LN metastases cervical cancer Tumors staging like IA, IB II A, II B, IIIA and IVA in cervical cancer with 95% CI. After pooling all studies, of CT, MRI, PET and PET/CT for Breast cancer the Forest plot of sensitivity and specificity of CT 0.87 (0.85, 0.89), 0.35 (0.33,0.38) MRI 0.97 (0.94, 0.98), 0.88(0.84, 0.91) PET 0.89 (0.86,0.90) 0.91(0.89, 0.93) and PET/CT 0.86(0.83, 0.88) 0.91(0.89, 0.93) in detecting local recurrences, lesion basis, distant metastases, and breast lesions in Breast cancer with 95 % CI After pooling all studies, of CT, MRI, PET and PET/CT for Head and Neck cancer the Forest plot of sensitivity and specificity of CT 0.81(0.77,0.85), 0.72(0.70, 0.74) MRI 0.77(0.74,0.79), 0.78(0.77,0.79) PET 0.20 (0.16, 0.25) 0.94(0.92, 0.96) and PET/CT 0.84(0.82,0.86) 0.88(0.86,0.89) in detecting Lymph node metastasis, detection of recurrence in patients and detecting neck levels I, II, and III with head and neck cancer Head and neck cancer with 95 % CI. After pooling all studies of CT, MRI, PET and PET/CT for Gastric cance
Download article email to a friend

Cite This Article

  • ISSN: 2349-6002
  • Volume: 7
  • Issue: 10
  • PageNo: 89-99

Clinical Effectiveness of PET/CT, PET, CT and MRI for Breast, Cervical, Head and Neck, Gastric and Lung Cancer-A Systematic Review and Meta-analysis

Related Articles

Impact Factor
8.01 (Year 2024)
UGC Approved
Journal no 47859

Join Our IPN

IJIRT Partner Network

Submit your research paper and those of your network (friends, colleagues, or peers) through your IPN account, and receive 800 INR for each paper that gets published.

Join Now

Latest Publication

Archive

View More

Recent Conferences

NCSEM 2024

National Conference on Sustainable Engineering and Management - 2024 Last Date: 15th March 2024

Submit inquiry