Phytochemical, Antioxidant Antibacterial and Mutagenic property (AMES) in vitro analysis of Strobilanthes Barbatus
Author(s):
Farzana Hilal, Aysha O.S
DOI Number:
10.6084/m9.figshare.14564382
Keywords:
Strobilanthes barbatus, antioxidant activity, AMES assay, and antibacterial activity.
Abstract
Strobilanthes barbatus (SB) was analyzed for its phytochemical, antioxidant, antibacterial, and mutagenic properties. The shade-dried powdered material of leaves was evaluated by phytochemical analysis. The antibacterial activity of a test compound extract of (Strobilanthes barbatus) against Streptococcus pyogenes was assessed by an automated BD Phoenix system and compared to a Resazurin microtitre assay (REMA) plate using left-over throat swab samples of arthritis patients. The antioxidant activity of the extract was evaluated by DPPH assay, phosphomolybdenum assay, and Ferric reducing assay. The results of the preliminary phytochemical analysis revealed the detection of alkaloids, flavonoids, tannins, saponins, sterols, and triterpenoids. The Strobilanthes extract was shown to exhibit marked dose-dependent radical scavenging, ferric reducing potential and antibacterial effect against Streptococcus pyogenes and have not provided any mutagenic effect. Thus, extract of SB was concluded as promising in terms of antibacterial and antioxidant potential with no mutagenic property. Further studies are to be undertaken to investigate their biological activities in animal studies.
Article Details
Unique Paper ID: 151012

Publication Volume & Issue: Volume 7, Issue 11

Page(s): 728 - 735
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