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MICROWAVE ASSISTED TRICHLORO TRIAZINE CATALYZED SYNTHESIS OF 2-(4-((4-CHLOROPHENYL) SULFONYL) PHENYL)-5-PHENYLOXAZOLES

  • Unique Paper ID: 153946
  • Volume: 8
  • Issue: 9
  • PageNo: 292-297
  • Abstract:
  • Starting as an Amino acid (Hippuric acid) 1 cyclized by using cyanuric acid (TCT) as environmentally benign catalyst to 2-phenyloxazol-5(4H)-one 2 further treated with aromatic aldehyde Friedel-Craft reaction to benzoyl amino ketones 3 and finally cyclized gives good yields of 2-(4-((4-chlorophenyl) sulfonyl) phenyl)-5-phenyloxazoles 4a-h under microwave condition. The reaction performed in less time of reaction, cleaner no side product, good to excellent yield of product.
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Cite This Article

  • ISSN: 2349-6002
  • Volume: 8
  • Issue: 9
  • PageNo: 292-297

MICROWAVE ASSISTED TRICHLORO TRIAZINE CATALYZED SYNTHESIS OF 2-(4-((4-CHLOROPHENYL) SULFONYL) PHENYL)-5-PHENYLOXAZOLES

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