MICROWAVE ASSISTED TRICHLORO TRIAZINE CATALYZED SYNTHESIS OF 2-(4-((4-CHLOROPHENYL) SULFONYL) PHENYL)-5-PHENYLOXAZOLES

  • Unique Paper ID: 153946
  • Volume: 8
  • Issue: 9
  • PageNo: 292-297
  • Abstract:
  • Starting as an Amino acid (Hippuric acid) 1 cyclized by using cyanuric acid (TCT) as environmentally benign catalyst to 2-phenyloxazol-5(4H)-one 2 further treated with aromatic aldehyde Friedel-Craft reaction to benzoyl amino ketones 3 and finally cyclized gives good yields of 2-(4-((4-chlorophenyl) sulfonyl) phenyl)-5-phenyloxazoles 4a-h under microwave condition. The reaction performed in less time of reaction, cleaner no side product, good to excellent yield of product.

Copyright & License

Copyright © 2025 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{153946,
        author = {Omprakash S. Chavan},
        title = {MICROWAVE ASSISTED TRICHLORO TRIAZINE CATALYZED SYNTHESIS OF 2-(4-((4-CHLOROPHENYL) SULFONYL) PHENYL)-5-PHENYLOXAZOLES },
        journal = {International Journal of Innovative Research in Technology},
        year = {},
        volume = {8},
        number = {9},
        pages = {292-297},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=153946},
        abstract = {Starting as an Amino acid (Hippuric acid) 1 cyclized by using cyanuric acid (TCT) as environmentally benign catalyst to 2-phenyloxazol-5(4H)-one 2 further treated with aromatic aldehyde Friedel-Craft reaction to benzoyl amino ketones 3 and finally cyclized gives good yields of 2-(4-((4-chlorophenyl) sulfonyl) phenyl)-5-phenyloxazoles 4a-h under microwave condition. The reaction performed in less time of reaction, cleaner no side product, good to excellent yield of product.},
        keywords = {Hippuric acid, Oxazole, Trichloro triazine (TCT), Microwave method},
        month = {},
        }

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