Fabrication of Excipients Free Tablet using Biodegradable Cellulose Paper
Author(s):
Arup Kabiraj, Aritra Kar, Ashvini Kumar, Atindriya Guha, Bhupendra Bhandari, Aishorya Dhakal, Arnab Bagchi
Keywords:
Cellulose Paper, Paracetamol, SmartFilm Technology.
Abstract
In this study, the potential for compressing cellulose paper into tablets was rigorously examined. Results demonstrated that paper may be utilized to make tablets, regardless of the type of paper used. The pills have a sleek, polished appearance. The pharmaceutical quality was satisfactory; all of the pills met the Indian Pharmacopeia's standards for tablets. Compressing drug-loaded paper resulted in the creation of drug-loaded tablets. The quality of the medication was unaffected by drug loading. However, the uncoated pills had a very quick disintegration rate, causing severe swelling when they came in contact with water, which could make it difficult for people to take them following oral administration. Tablets were effectively covered with a polymer film to prevent swelling, which not only prevented swelling but also caused a rapid disintegration in simulated gastric juice. In reality, paper-based tablets offer an innovative and promising method for enhancing oral medication delivery. According to the Indian Pharmacopeia, they can be simply synthesized without any additional excipients and have medicinal purity.
Article Details
Unique Paper ID: 156377

Publication Volume & Issue: Volume 9, Issue 3

Page(s): 451 - 456
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