Synthesis, Characterisation and Anticonvulsive Evaluation of Pyridine & Pyrimidine Hydantoins

Synthesis, Characterisation and Anticonvulsive Evaluation of Pyridine & Pyrimidine Hydantoins
Author(s):
Dr. Sangeeta Kamthan
Keywords:
anticonvulsive activity, hydantoins, Pyridine, Pyrimidine
Abstract
Heterocyclic compounds having Nitrogen as hetero-atom are highly reactive and possess various pharmacological activities. Hydantoins of pyridine and pyrimidine were synthesized via chloro-acetyl derivatives. The synthesized compounds were characterized by means of their IR and purity checked by the analysis. The compounds were evaluated for anticonvulsant activity by maximal electro-shock method and chemo-shock. They were found to possess significant activity.
Article Details
Unique Paper ID: 157006 Publication Volume & Issue: Volume 9, Issue 5 Page(s): 601 - 604
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