ANTIUROLITHIATIC ACTIVITY OF ETHANOLIC EXTRACT OF CUCUMIS SATIVUS FRUIT IN WISTAR RATS

GADDAM SUSHMA

ANTIUROLITHIATIC ACTIVITY OF ETHANOLIC EXTRACT OF CUCUMIS SATIVUS FRUIT IN WISTAR RATS

Authors: GADDAM SUSHMA

Unique Paper ID: 158992
Volume: 9
Issue: 11
PageNo: 108-112

Keywords: Cucumis sativus Antiurolithiatic activity Allopurinol and Ethylene glycol (0.75 % v/v)

Abstract:
The present study explores the antiurolithiatic activity of an ethanolic extract of the Cucumis Sativus (CS) fruit in Wistar rats. Ethylene glycol (0.75% v/v) induced calculi in Wistar rats. They have assessed various parameters like biochemical estimations of serum, urine, and kidney tissue homogenate and histopathological studies of a kidney. The treatment with doses of 200 mg/kg and 400 mg/kg of ethanolic extract of CS exerts dose-dependent anti-urolithic activity. A significant reduction in the deposition of kidney stone-forming constituents like calcium, oxalate, and phosphate was found in the kidneys. The Wistar ratâ€™s kidney sections showed the presence of crystals, dilatation of tubules tubulorrhexis, and the epithelial recovered.

Download article

email to a friend

Cite This Article

ISSN: 2349-6002
Volume: 9
Issue: 11
PageNo: 108-112

ANTIUROLITHIATIC ACTIVITY OF ETHANOLIC EXTRACT OF CUCUMIS SATIVUS FRUIT IN WISTAR RATS

Available:https://ijirt.org/Article?manuscript=158992

03 Oct, 2024

Phytochemical Investigation, Antioxidant and Antimicrobial Activities of Terminalia Bellerica Fruit Extract

09 Apr, 2024

Formulation development, in vitro and in vivo studies of eprosartan mesylate loaded solid lipid nanoparticles for improved bioavailability

01 Apr, 2023

DEVELOPMENT AND CHARACTERIZATION OF QUINAPRIL CO-CRYSTALS USING NEUTRACEUTICALS AS CO-FORMERS

24 Jan, 2023

FORMULATION AND IN VITRO EVALUATION OF SUSTAINED RELEASE TABLETS OF VENLAFAXINE HCl

24 Aug, 2021

FORMULATION AND EVALUATION OF PRESS-COATED PULSATILE DELIVERY OF FLURBIPROFEN TABLETS

Impact Factor
8.01 (Year 2024)

UGC Approved
Journal no 47859

Join Our IPN

IJIRT Partner Network

Submit your research paper and those of your network (friends, colleagues, or peers) through your IPN account, and receive 800 INR for each paper that gets published.

Join Now

Latest Publication

Recent Conferences

NCSEM 2024

National Conference on Sustainable Engineering and Management - 2024 Last Date: 15th March 2024

Submit inquiry