During the past decades, the microbial world have provided many important bioactive compounds of high commercial value. Over 5000 antibiotics have been identified from the cultures of Gram-positive, Gram-negative and filamentous fungi, but only about 100 antibiotics alone have been used commercially to treat human, animal, and plant diseases. These searches have been remarkably successful, and approximately two-thirds of naturally occurring antibiotics have been isolated from microbes. The need for less toxic, more potent antibiotics from noninfective organisms. Microbes, which are prolific producers of antibiotics and important suppliers to the pharmaceutical industry, can produce a wide variety of secondary metabolites. Consequently, they are continuing to be routinely screened for new bioactive substances.
Article Details
Unique Paper ID: 160181
Publication Volume & Issue: Volume 9, Issue 12
Page(s): 1243 - 1248
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