Formulation and Evaluation of Fast-Dissolving Tablets Incorporating Salbutamol Sulphate and Cetirizine Hydrochloride: An Innovative Strategy for Enhancing Medication Delivery in Children and Elderly Patient

Ms. Priyanka Anil Ahire; Krupa Abhijit Khadakban; Ms. Nida Ali; Dr. Ganesh Bhagawat Giri; Mr. Amit Sureshrao Sontakke; Ms. Prajita Jivan Tayade

Formulation and Evaluation of Fast-Dissolving Tablets Incorporating Salbutamol Sulphate and Cetirizine Hydrochloride: An Innovative Strategy for Enhancing Medication Delivery in Children and Elderly Patient

Authors: Ms. Priyanka Anil Ahire, Krupa Abhijit Khadakban, Ms. Nida Ali, Dr. Ganesh Bhagawat Giri, Mr. Amit Sureshrao Sontakke, Ms. Prajita Jivan Tayade

Unique Paper ID: 182006
Volume: 12
Issue: 2
PageNo: 455-461

Keywords: Fast-dissolving tablets Salbutamol sulphate Cetirizine hydrochloride Pediatric drug delivery Geriatric drug delivery Superdisintegrants Patient compliance.

Abstract:
Fast-dissolving tablets (FDTs) offer a patient-friendly dosage form, especially beneficial for pediatric and geriatric populations who often struggle with swallowing conventional tablets. This study aims to formulate and evaluate FDTs containing salbutamol sulphate, a bronchodilator, and cetirizine hydrochloride, an antihistamine, to facilitate rapid onset of action and improve patient compliance. Various superdisintegrants and excipients were screened to optimize tablet properties. The prepared tablets were evaluated for weight uniformity, hardness, friability, disintegration time, drug content, dissolution profile, and stability. Results demonstrated that the optimized formulation rapidly disintegrated within 30 seconds and exhibited satisfactory mechanical strength and drug release, highlighting its potential for improved drug delivery in target populations.

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ISSN: 2349-6002
Volume: 12
Issue: 2
PageNo: 455-461

Formulation and Evaluation of Fast-Dissolving Tablets Incorporating Salbutamol Sulphate and Cetirizine Hydrochloride: An Innovative Strategy for Enhancing Medication Delivery in Children and Elderly Patient

Available:https://ijirt.org/Article?manuscript=182006

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