Excipients are added in formulations to facilitate the production process, provide stability, increase bioavailability, or support safety and patient acceptance. Both the efficacy and the standard of a pharmaceutical product are significantly affected by the selection of the excipients. Combining two or more excipients through physical co-processing that does not produce covalent bonds is known as co-processed excipients. Co-processed excipients are capable of functions that sample blending is unable to provide. When compared to individual excipients, these excipients work better because of flow characteristics, compressibility, with reduced lubricant sensitivity. Marketed products such as Ludi press, Ludi flash, and Prosolv, among others, have already demonstrated their value in the marketplace by lowering the cost of the product and the number of excipients while keeping the formulation's effectiveness
Article Details
Unique Paper ID: 162028
Publication Volume & Issue: Volume 10, Issue 7
Page(s): 266 - 272
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