Microbes and Medicine: A Review of Therapeutic Applications
Author(s):
Kartiki Rangnath Desai
Keywords:
Clinical considerations, CRISPR-Cas, Future directions, Medicine, Microbes, Phage therapy, Probiotics, Synthetic biology, Therapeutic applications
Abstract
Microbes play a pivotal role in modern medicine, contributing to therapeutic advancements in diverse ways. This comprehensive review explores the myriad applications of microbes in medicine, ranging from their roles as sources of therapeutic agents to their utilization in various treatment modalities. The review begins with an overview of the microbial sources of therapeutic agents, encompassing natural products such as antibiotics, antifungals, and antivirals, as well as engineered microbes engineered to produce biologics and serve as gene therapy vectors. Furthermore, microbial therapy approaches, including probiotics, phage therapy, and microbial immunotherapy, are examined in detail, elucidating their mechanisms of action and clinical applications. In addition, the review delves into microbial engineering strategies, such as synthetic biology approaches and the utilization of CRISPR-Cas systems, for the development of tailored microbial therapies. Clinical considerations and challenges, such as safety concerns and regulatory frameworks, are also explored, providing insights into the current landscape of microbial therapy research. Finally, future directions in microbial therapy research are discussed, highlighting emerging trends and the potential impact on future medical practices. Through this review, the significant contributions of microbes to the field of medicine are underscored, emphasizing the promising prospects of microbial-based therapies in addressing various health challenges.
Article Details
Unique Paper ID: 162272

Publication Volume & Issue: Volume 10, Issue 9

Page(s): 66 - 73
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