Microwave-Assisted Synthesis of Nitrogen Heterocycles: Advancements, Mechanistic Insights, and Biological Evaluations
Sangeeta Kumari, P. K. Mishra
Microwave-assisted synthesis has emerged as a revolutionary technique within organic chemistry, revolutionizing the fabrication of a wide array of nitrogen heterocycles. This abstract provides an overview of the synthesis of nitrogen-containing heterocyclic compounds, utilizing microwave irradiation as a central methodology. By harnessing the power of microwave irradiation, reaction rates are accelerated, leading to enhanced yields and superior selectivity compared to conventional thermal methods. The synthesis of nitrogen heterocycles, including but not limited to pyrazoles, pyridines, triazoles, and pyrimidines, under microwave conditions will be explored, emphasizing the inherent advantages of this approach in terms of reaction efficiency and environmental impact mitigation. Furthermore, the elucidation of mechanistic insights pertaining to microwave-assisted synthesis of nitrogen heterocycles will be discussed, aiming to provide a comprehensive understanding of the underlying reaction pathways. Ultimately, microwave-assisted synthesis stands as a promising methodology for the swift and sustainable fabrication of nitrogen heterocyclic compounds, with broad-reaching applications spanning pharmaceuticals, agrochemicals, and materials science
Article Details
Unique Paper ID: 163216

Publication Volume & Issue: Volume 10, Issue 10

Page(s): 1038 - 1041
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