AN EFFICIENT SYNTHESIS OF SCHIFFS BASE CONTAINING BENZIMIDAZOLE MOIETY CATALYZED BY TRICHLORO SALICYLIC ACID
Author(s):
Dr.N.KRISHNARAO, K.Naveenkumar
Keywords:
O-phenyldiamine, CNBr, 2-aminobenzimidazole, Trichloro Salicylic Acid, substituted aryl aldehydes, Schiff bases, Bioevluation.
Abstract
An efficient method for the synthesis for a novel Schiff bases from 2-amino benzimidazoles with P-substituted aryl aldehyde by using Trichloro Salicylic Acid in organic solvent at room temperature. The intermediate moiety (2-amino Benzimidazole) can be synthesized from o-phenyl diamine with cyano bromide in the presence of acid medium. All the newly synthesized derivatives were evaluated by the advanced spectroscopic data (1HNMR, 13CNMR and LCMS) and also structural determination titled compounds were calculated by elemental analysis. In addition to all newly compounds were screened by their anti-microbial activity.
Article Details
Unique Paper ID: 163634

Publication Volume & Issue: Volume 10, Issue 11

Page(s): 2503 - 2507
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