Author Login IJIRT Partner Network (IPN) Login

Formulation and evaluation of mucoadhesive tablet of Ranolizine

  • Unique Paper ID: 165853
  • Volume: 11
  • Issue: 1
  • PageNo: 1876-1884
  • Abstract:
  • Ranolazine, a promising drug for the management of chronic angina, poses challenges in achieving sustained release and localizing its effect at the target site due to its short half-life and frequent dosing regimen. This study aimed to develop mucoadhesive tablets of ranolazine to enhance its bioavailability, prolong its release, and improve patient compliance. The tablets were formulated using various polymers, including hydroxypropyl methylcellulose (HPMC), Carbopol, and sodium alginate, to achieve the desired mucoadhesive properties. The formulations were characterized for drug content, swelling index, mucoadhesive strength, in vitro drug release, and ex vivo mucoadhesion time. The optimized formulation exhibited satisfactory characteristics, with prolonged drug release over 12 hours, strong mucoadhesive properties, and enhanced bioavailability. In conclusion, mucoadhesive tablets of ranolazine hold promise as a potential dosage form for improving therapeutic outcomes and patient adherence in the treatment of chronic angina.
Download article email to a friend

Cite This Article

  • ISSN: 2349-6002
  • Volume: 11
  • Issue: 1
  • PageNo: 1876-1884

Formulation and evaluation of mucoadhesive tablet of Ranolizine

Related Articles

16 Dec, 2023

Sale And Marketing of different System of Medicines

Read More
Impact Factor
8.01 (Year 2024)
UGC Approved
Journal no 47859

Join Our IPN

IJIRT Partner Network

Submit your research paper and those of your network (friends, colleagues, or peers) through your IPN account, and receive 800 INR for each paper that gets published.

Join Now

Latest Publication

Archive

View More

Recent Conferences

NCSEM 2024

National Conference on Sustainable Engineering and Management - 2024 Last Date: 15th March 2024

Submit inquiry