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Develop and Evaluate Compression Coating Technology

  • Unique Paper ID: 166552
  • Volume: 11
  • Issue: 2
  • PageNo: 1264-1269
  • Abstract:
  • Tablets are indeed the most popular solid dosage form for oral administration. One category of tablet formulations that has gained remarkable importance in drug therapeutics owing to various benefits it offers is controlled or modified release formulations. Although less popular, compression coating technology gained increased interest in the recent years for creating modified released products. It involves the compaction of granular materials around a preformed tablet core using specially designed tableting equipment. Compression coating is a dry process. This type of tablet (compression coated tablet) has two parts, internal core and surrounding coat. The core is small porous tablet and prepared on one turret. After tablet core manufacture it is transferred (centrally positioned) to another slightly larger die that is partially filled with coating powder. More coating powder is filled on the top of the core and compressed again resulting in tablet with in tablet. Mechanically, it is a complex process, as the tablet may be tilted when transferred to the second die cavity. Mostly, the coat is water soluble and disintegrates easily after swallowing, in order to achieve immediate release product.
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Cite This Article

  • ISSN: 2349-6002
  • Volume: 11
  • Issue: 2
  • PageNo: 1264-1269

Develop and Evaluate Compression Coating Technology

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